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2.CRISPR KO

2.CRISPR KO

CRISPR is used to cleave two targets at a certain distance in the genome, and the sequence between these two targets is knocked out (KO) through NHEJ, resulting in the loss of function.
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Scheme：



Advantages：

◉Designs can minimize the impact on neighboring genes, and ensure the specificity of knockout..

◉High-efficiency, with experience in successfully KO genomic sequences of over 100kb.


Technical Service Process：